TAMI-29. MULTIFACTORIAL UPREGULATION OF ID1 DRIVES DIPG INVASIVENESS AND IS THERAPEUTICALLY TARGETABLE

Diffuse intrinsic pontine gliomas (DIPGs) are lethal brain tumors with no effective therapies other than radiation. Inhibitor of DNA binding (ID) proteins, key regulators of lineage commitment during embryogenesis, are implicated in tumorigenesis in multiple human cancers. Prior work showed that rec...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Main Authors: Nand Yadav, Viveka, Harris, Micah K, Stallard, Stefanie, Woo, Rinette, Siddaway, Robert, Qin, Tingting, Cummings, Jessica, Mullan, Brendan, Miklja, Zachary, Siada, Ruby, Ravindran, Ramya, Cao, Xuhong, Pasternak, Amy, Castro, Maria G, Lowenstein, Pedro, Mody, Rajen, Chinnaiyan, Arul, Hawkins, Cynthia, Desprez, Pierre, McAllister, Sean, Venneti, Sriram, Koschmann, Carl
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
Assuntos:
Tumor Microenvironment/Angiogenesis/Metabolism/Invasion
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651395/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.917
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