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STEM-29. THE HISTONE VARIANT macroH2A2 ORCHESTRATES AN ACTIONABLE CHROMATIN PROGRAM OF STEMNESS IN GLIOBLASTOMA

Glioblastoma cells with the crucial stemness property of self-renewal constitute therapy-resistant reservoirs that seed tumor relapse. Effective targeting of these cells in clinical settings has been hampered by their relative quiescence, which invalidates the cell replication bias of most current t...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Neuro Oncol
Päätekijät: Nikolic, Ana, Bobyn, Anna, Ellestad, Katrina, Lun, Xueqing, Johnston, Michael, Gafuik, Christopher, Zemp, Franz, Ninkovic, Nicoletta, Berger, Daniel, Brownsey, Duncan, Dirks, Peter, Derksen, Darren, Senger, Donna, Chan, Jennifer, Mahoney, Douglas, Gallo, Marco
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651160/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.846
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