STEM-29. THE HISTONE VARIANT macroH2A2 ORCHESTRATES AN ACTIONABLE CHROMATIN PROGRAM OF STEMNESS IN GLIOBLASTOMA

Glioblastoma cells with the crucial stemness property of self-renewal constitute therapy-resistant reservoirs that seed tumor relapse. Effective targeting of these cells in clinical settings has been hampered by their relative quiescence, which invalidates the cell replication bias of most current t...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Neuro Oncol
Autores principales: Nikolic, Ana, Bobyn, Anna, Ellestad, Katrina, Lun, Xueqing, Johnston, Michael, Gafuik, Christopher, Zemp, Franz, Ninkovic, Nicoletta, Berger, Daniel, Brownsey, Duncan, Dirks, Peter, Derksen, Darren, Senger, Donna, Chan, Jennifer, Mahoney, Douglas, Gallo, Marco
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2020
Materias:
Cancer Stem Cells
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651160/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.846
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares