STEM-29. THE HISTONE VARIANT macroH2A2 ORCHESTRATES AN ACTIONABLE CHROMATIN PROGRAM OF STEMNESS IN GLIOBLASTOMA

Glioblastoma cells with the crucial stemness property of self-renewal constitute therapy-resistant reservoirs that seed tumor relapse. Effective targeting of these cells in clinical settings has been hampered by their relative quiescence, which invalidates the cell replication bias of most current t...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Nikolic, Ana, Bobyn, Anna, Ellestad, Katrina, Lun, Xueqing, Johnston, Michael, Gafuik, Christopher, Zemp, Franz, Ninkovic, Nicoletta, Berger, Daniel, Brownsey, Duncan, Dirks, Peter, Derksen, Darren, Senger, Donna, Chan, Jennifer, Mahoney, Douglas, Gallo, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Cancer Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651160/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.846
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