STEM-29. THE HISTONE VARIANT macroH2A2 ORCHESTRATES AN ACTIONABLE CHROMATIN PROGRAM OF STEMNESS IN GLIOBLASTOMA

Glioblastoma cells with the crucial stemness property of self-renewal constitute therapy-resistant reservoirs that seed tumor relapse. Effective targeting of these cells in clinical settings has been hampered by their relative quiescence, which invalidates the cell replication bias of most current t...

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Publicat a:Neuro Oncol
Autors principals: Nikolic, Ana, Bobyn, Anna, Ellestad, Katrina, Lun, Xueqing, Johnston, Michael, Gafuik, Christopher, Zemp, Franz, Ninkovic, Nicoletta, Berger, Daniel, Brownsey, Duncan, Dirks, Peter, Derksen, Darren, Senger, Donna, Chan, Jennifer, Mahoney, Douglas, Gallo, Marco
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Cancer Stem Cells
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651160/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.846
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