DDRE-34. TRIBBLES-1 (TRIB1) PSEUDOKINASE PROMOTES SURVIVAL OF GBM CELLS BY DECREASING RT/TMZ INDUCED APOPTOSIS

INTRODUCTION: Glioblastoma (GBM) is the most aggressive form of glioma with a mean survival of 12 to 15 months after diagnosis. The current therapy involves administration of radiation therapy and temozolomide (TMZ). Due to poor survival outcome, new druggable therapeutic targets need to be identifi...

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發表在:Neuro Oncol
Main Authors: Singh, Karnika, Han, Chunhua, Fleming, Jessica, McElroy, Joseph, Bell, Erica, Robe, Pierre, Haque, S Jaharul, Chakravarti, Arnab
格式: Artigo
語言:Inglês
出版: Oxford University Press 2020
主題:
Drug Discovery, Drug Resistance
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651042/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.279
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