DDRE-34. TRIBBLES-1 (TRIB1) PSEUDOKINASE PROMOTES SURVIVAL OF GBM CELLS BY DECREASING RT/TMZ INDUCED APOPTOSIS

INTRODUCTION: Glioblastoma (GBM) is the most aggressive form of glioma with a mean survival of 12 to 15 months after diagnosis. The current therapy involves administration of radiation therapy and temozolomide (TMZ). Due to poor survival outcome, new druggable therapeutic targets need to be identifi...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Singh, Karnika, Han, Chunhua, Fleming, Jessica, McElroy, Joseph, Bell, Erica, Robe, Pierre, Haque, S Jaharul, Chakravarti, Arnab
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Drug Discovery, Drug Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651042/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.279
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