טוען...
Engineering and Preclinical Evaluation of Western Reserve Oncolytic Vaccinia Virus Expressing A167Y Mutant Herpes Simplex Virus Thymidine Kinase
Viral replication of thymidine kinase deleted (tk(−)) vaccinia virus (VV) is attenuated in resting normal cells, enabling cancer selectivity, however, replication potency of VV-tk(−) appears to be diminished in cancer cells. Previously, we found that wild-type herpes simplex virus (HSV)-tk (HSV-tk)...
שמור ב:
| הוצא לאור ב: | Biomedicines |
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| Main Authors: | , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
MDPI
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7650665/ https://ncbi.nlm.nih.gov/pubmed/33081279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8100426 |
| תגים: |
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