CBIO-19. LOW GLOBAL HISTONE H4 ACETYLATION LEVELS REVEAL CANDIDATE QUIESCENT CELL POPULATIONS IN GLIOMA AND DISTINGUISH TUMORS BY GRADE

Current standard of care therapy for glioblastoma (GBM) includes cytoreduction followed by ablative therapies that target rapidly dividing cell types. However, the presence of quiescent-like/G0 states, therefore, represents a natural reservoir of tumor cells that are resistant to current treatments....

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Mihalas, Anca, Feldman, Heather, Patel, Anoop, Paddison, Patrick
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Cell Biology (Cell Cycle Regulation, DNA Repair/Modulation)
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650492/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.079
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