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CBIO-19. LOW GLOBAL HISTONE H4 ACETYLATION LEVELS REVEAL CANDIDATE QUIESCENT CELL POPULATIONS IN GLIOMA AND DISTINGUISH TUMORS BY GRADE

Current standard of care therapy for glioblastoma (GBM) includes cytoreduction followed by ablative therapies that target rapidly dividing cell types. However, the presence of quiescent-like/G0 states, therefore, represents a natural reservoir of tumor cells that are resistant to current treatments....

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Main Authors: Mihalas, Anca, Feldman, Heather, Patel, Anoop, Paddison, Patrick
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650492/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.079
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