CBIO-03. ATRX LOSS IN GLIOMA RESULTS IN EPIGENETIC DYSREGULATION OF CELL CYCLE PHASE TRANSITION

Gliomas are a leading cause of cancer mortality in children and adults, and new targeted therapies are desperately needed. ATRX is a chromatin remodeling protein that is recurrently mutated in H3F3A-mutant pediatric glioblastoma (GBM) and IDH-mutant grade 2/3 adult glioma. We previously showed that...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Mullan, Brendan, Qin, Tingting, Siada, Ruby, Ravindran, Ramya, Thomas, Chase, Harris, Micah, Muruganand, Ashwat, Pyaram, Kalyani, Miklja, Zachary, Reiber, Mary, Garcia, Taylor, Tran, Dustin, Danussi, Carla, Brosnan-Cashman, Jackie, Pratt, Drew, Zhao, Xinyi, Rehemtulla, Alnawaz, Sartor, Maureen, Venneti, Sriram, Meeker, Alan, Huse, Jason, Morgan, Meredith, Lowenstein, Pedro, Castro, Maria, Yadav, Viveka Nand, Koschmann, Carl
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Cell Biology (Cell Cycle Regulation, DNA Repair/Modulation)
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650371/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.063
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