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Identification of Hot Spots in the Variola Virus Complement Inhibitor (SPICE) for Human Complement Regulation

Variola virus, the causative agent of smallpox, encodes a soluble complement regulator named SPICE. Previously, SPICE has been shown to be much more potent in inactivating human complement than the vaccinia virus complement control protein (VCP), although they differ only in 11 amino acid residues....

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Detalhes bibliográficos
Main Authors: Yadav, Viveka Nand, Pyaram, Kalyani, Mullick, Jayati, Sahu, Arvind
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268448/
https://ncbi.nlm.nih.gov/pubmed/18216095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01935-07
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