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Identification of Hot Spots in the Variola Virus Complement Inhibitor (SPICE) for Human Complement Regulation

Variola virus, the causative agent of smallpox, encodes a soluble complement regulator named SPICE. Previously, SPICE has been shown to be much more potent in inactivating human complement than the vaccinia virus complement control protein (VCP), although they differ only in 11 amino acid residues....

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Bibliografiske detaljer
Main Authors: Yadav, Viveka Nand, Pyaram, Kalyani, Mullick, Jayati, Sahu, Arvind
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268448/
https://ncbi.nlm.nih.gov/pubmed/18216095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01935-07
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