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Identification of Hot Spots in the Variola Virus Complement Inhibitor (SPICE) for Human Complement Regulation

Variola virus, the causative agent of smallpox, encodes a soluble complement regulator named SPICE. Previously, SPICE has been shown to be much more potent in inactivating human complement than the vaccinia virus complement control protein (VCP), although they differ only in 11 amino acid residues....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yadav, Viveka Nand, Pyaram, Kalyani, Mullick, Jayati, Sahu, Arvind
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268448/
https://ncbi.nlm.nih.gov/pubmed/18216095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01935-07
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