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Identification of Hot Spots in the Variola Virus Complement Inhibitor (SPICE) for Human Complement Regulation

Variola virus, the causative agent of smallpox, encodes a soluble complement regulator named SPICE. Previously, SPICE has been shown to be much more potent in inactivating human complement than the vaccinia virus complement control protein (VCP), although they differ only in 11 amino acid residues....

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Main Authors: Yadav, Viveka Nand, Pyaram, Kalyani, Mullick, Jayati, Sahu, Arvind
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268448/
https://ncbi.nlm.nih.gov/pubmed/18216095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01935-07
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