CBMT-42. A GENOME-WIDE CRISPR-Cas9 SCREEN FOR GENES REGULATING QUIESCENT-LIKE STATES IN GLIOBLASTOMA

Current standard of care therapy for glioblastoma (GBM) includes cytoreduction followed by ablative therapies that target rapidly dividing cell types. However, non-cycling, quiescent-like states (G0 phase cells) are present in both normal tissue and tumors and play important roles in maintaining het...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Feldman, Heather, Mihalas, Anca, Plaisier, Christopher, Patel, Anoop, Paddison, Patrick
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Cell Biology and Metabolism
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847714/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.164
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