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CBIO-14. ELUCIDATING THE MECHANISM OF TEMOZOLOMIDE-INDUCED ATR ACTIVATION IN MGMT-METHYLATED GLIOBLASTOMA MULTIFORME
Glioblastoma multiforme (GBM) is an aggressive, malignant brain tumor in adults. The current standard of care for GBM is surgical resection, radiation therapy and chemotherapy with temozolomide (TMZ). It is well established that GBM patients with a methylated MGMT promoter (MGMT-) who are treated wi...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7650457/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.074 |
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