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BIOM-38. PI3K/AKT/mTOR SIGNALING PATHWAY ACTIVITY IN IDH-MUTANT DIFFUSE GLIOMA

PI3K/AKT/mTOR signaling pathway activation is a common mechanism of tumor progression in diffuse lower grade glioma. Robust and accurate biomarkers are needed to stratify patients for therapies targeting this pathway. To investigate the potential of phosphoprotein quantification to provide a direct...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: Mohamed, Esraa, Kumar, Anupam, Hilz, Stephanie, Wang, Albert, Shai, Anny, Taylor, Jennie, Clarke, Jennifer, Molinaro, Annette, Lee, Julieann, Costello, Joseph, Solomon, David, Phillips, Joanna
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650385/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.037
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