Tissue expression of lactate transporters (MCT1 and MCT4) and prognosis of malignant pleural mesothelioma (brief report)

BACKGROUND: Malignant pleural mesothelioma (MPM) is an aggressive neoplasm of the pleura, mainly related to asbestos exposure. As in other solid tumors, malignant cells exhibit high glucose uptake and glycolytic rates with increased lactic acid efflux into the interstitial space. Lactate transport i...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Dell’Anno, Irene, Barone, Elisa, Mutti, Luciano, Rassl, Doris M., Marciniak, Stefan J., Silvestri, Roberto, Landi, Stefano, Gemignani, Federica
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650278/
https://ncbi.nlm.nih.gov/pubmed/32887638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02487-6
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