Drug-repositioning screening identified fludarabine and risedronic acid as potential therapeutic compounds for malignant pleural mesothelioma

Objectives Malignant pleural mesothelioma (MPM) is an occupational disease mainly due to asbestos exposure. Effective therapies for MPM are lacking, making this tumour type a fatal disease. Materials and Methods In order to meet this need and in view of a future “drug repositioning” approach, here w...

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Bibliografiske detaljer
Udgivet i:Invest New Drugs
Main Authors: Dell’Anno, Irene, Martin, Sarah A., Barbarino, Marcella, Melani, Alessandra, Silvestri, Roberto, Bottaro, Maria, Paolicchi, Elisa, Corrado, Alda, Cipollini, Monica, Melaiu, Ombretta, Giordano, Antonio, Luzzi, Luca, Gemignani, Federica, Landi, Stefano
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2020
Fag:
Preclinical Studies
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8068714/
https://ncbi.nlm.nih.gov/pubmed/33300108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-020-01040-y
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