Tissue expression of lactate transporters (MCT1 and MCT4) and prognosis of malignant pleural mesothelioma (brief report)

BACKGROUND: Malignant pleural mesothelioma (MPM) is an aggressive neoplasm of the pleura, mainly related to asbestos exposure. As in other solid tumors, malignant cells exhibit high glucose uptake and glycolytic rates with increased lactic acid efflux into the interstitial space. Lactate transport i...

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Publicado en:J Transl Med
Autores principales: Dell’Anno, Irene, Barone, Elisa, Mutti, Luciano, Rassl, Doris M., Marciniak, Stefan J., Silvestri, Roberto, Landi, Stefano, Gemignani, Federica
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650278/
https://ncbi.nlm.nih.gov/pubmed/32887638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02487-6
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