“TRUPATH, an Open-Source Biosensor Platform for Interrogating the GPCR Transducerome”

G protein-coupled receptors (GPCRs) remain major drug targets despite our incomplete understanding of how they signal through 16 non-visual G protein signal transducers (collectively named the transducerome) to exert their actions. To address this gap, we developed an open-source suite of 14 optimiz...

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Publicado en:Nat Chem Biol
Main Authors: Olsen, Reid H.J., DiBerto, Jeffrey F., English, Justin G., Glaudin, Alexis M., Krumm, Brian E., Slocum, Samuel T., Che, Tao, Gavin, Ariana C., McCorvy, John D., Roth, Bryan L., Strachan, Ryan T.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7648517/
https://ncbi.nlm.nih.gov/pubmed/32367019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-020-0535-8
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