“TRUPATH, an Open-Source Biosensor Platform for Interrogating the GPCR Transducerome”

G protein-coupled receptors (GPCRs) remain major drug targets despite our incomplete understanding of how they signal through 16 non-visual G protein signal transducers (collectively named the transducerome) to exert their actions. To address this gap, we developed an open-source suite of 14 optimiz...

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Publicat a:Nat Chem Biol
Autors principals: Olsen, Reid H.J., DiBerto, Jeffrey F., English, Justin G., Glaudin, Alexis M., Krumm, Brian E., Slocum, Samuel T., Che, Tao, Gavin, Ariana C., McCorvy, John D., Roth, Bryan L., Strachan, Ryan T.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7648517/
https://ncbi.nlm.nih.gov/pubmed/32367019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-020-0535-8
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