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Detergent screening of a GPCR using serial and array biosensor technologies
We describe the benefits and limitations of two biosensor approaches for screening solubilization conditions for G-protein-coupled receptors. Assays designed for a serially processing instrument (Biacore 2000/3000/T100) and an array platform (Biacore Flexchip) were used to examine how effectively 96...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2669081/ https://ncbi.nlm.nih.gov/pubmed/19135021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2008.12.011 |
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