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The nuclear pore primes recombination-dependent DNA synthesis at arrested forks by promoting SUMO removal
Nuclear Pore complexes (NPCs) act as docking sites to anchor particular DNA lesions facilitating DNA repair by elusive mechanisms. Using replication fork barriers in fission yeast, we report that relocation of arrested forks to NPCs occurred after Rad51 loading and its enzymatic activity. The E3 SUM...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7648084/ https://ncbi.nlm.nih.gov/pubmed/33159083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19516-z |
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