The nuclear pore primes recombination-dependent DNA synthesis at arrested forks by promoting SUMO removal

Nuclear Pore complexes (NPCs) act as docking sites to anchor particular DNA lesions facilitating DNA repair by elusive mechanisms. Using replication fork barriers in fission yeast, we report that relocation of arrested forks to NPCs occurred after Rad51 loading and its enzymatic activity. The E3 SUM...

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Kramarz, Karol, Schirmeisen, Kamila, Boucherit, Virginie, Ait Saada, Anissia, Lovo, Claire, Palancade, Benoit, Freudenreich, Catherine, Lambert, Sarah A. E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7648084/
https://ncbi.nlm.nih.gov/pubmed/33159083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19516-z
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