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A SUMO-dependent feedback loop senses and controls the biogenesis of nuclear pore subunits

While the activity of multiprotein complexes is crucial for cellular metabolism, little is known about the mechanisms that collectively control the expression of their components. Here, we investigate the regulations targeting the biogenesis of the nuclear pore complex (NPC), the macromolecular asse...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Rouvière, Jérôme O., Bulfoni, Manuel, Tuck, Alex, Cosson, Bertrand, Devaux, Frédéric, Palancade, Benoit
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916902/
https://ncbi.nlm.nih.gov/pubmed/29695777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03673-3
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