Expression, purification and characterization of α-synuclein fibrillar specific scFv from inclusion bodies

Aggregation of α-synuclein (α-syn) has been implicated in multiple neurodegenerative disorders including Parkinson’s disease (PD), dementia with Lewy bodies (DLB) and multiple system atrophy (MSA), collectively grouped as synucleinopathies. Recently, recombinant antibody fragments (Fab, scFvs and di...

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Udgivet i:PLoS One
Main Authors: Gupta, Vijay, Sudhakaran, Indulekha P., Islam, Zeyaul, Vaikath, Nishant N., Hmila, Issam, Lukacsovich, Tamas, Kolatkar, Prasanna R., El-Agnaf, Omar M. A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7647061/
https://ncbi.nlm.nih.gov/pubmed/33156828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0241773
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