Expression, purification and characterization of α-synuclein fibrillar specific scFv from inclusion bodies

Aggregation of α-synuclein (α-syn) has been implicated in multiple neurodegenerative disorders including Parkinson’s disease (PD), dementia with Lewy bodies (DLB) and multiple system atrophy (MSA), collectively grouped as synucleinopathies. Recently, recombinant antibody fragments (Fab, scFvs and di...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gupta, Vijay, Sudhakaran, Indulekha P., Islam, Zeyaul, Vaikath, Nishant N., Hmila, Issam, Lukacsovich, Tamas, Kolatkar, Prasanna R., El-Agnaf, Omar M. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7647061/
https://ncbi.nlm.nih.gov/pubmed/33156828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0241773
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