Fibrillar form of α-synuclein-specific scFv antibody inhibits α-synuclein seeds induced aggregation and toxicity

Synucleinopathies including Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA) are characterized by pathological accumulation of α-synuclein (α-syn). Amongst the various approaches attempting to tackle the pathological features of synucleinopathies, antibody...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Gupta, Vijay, Salim, Safa, Hmila, Issam, Vaikath, Nishant N., Sudhakaran, Indulekha P., Ghanem, Simona S., Majbour, Nour K., Abdulla, Sara A., Emara, Mohamed M., Abdesselem, Houari B., Lukacsovich, Tamas, Erskine, Daniel, El-Agnaf, Omar M. A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7235225/
https://ncbi.nlm.nih.gov/pubmed/32424162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65035-8
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