Identification of a signalling mechanism by which the microbiome regulates Th17 cell-mediated depressive-like behaviors in mice

Microbiota dysbiosis has been linked to major depressive disorder, but the mechanisms whereby the microbiota modulates mood remain poorly understood. We show that Segmented filamentous bacteria (SFB)-deficient mice are resilient to the induction of depressive-like behavior, and are re-sensitized whe...

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Publicat a:Am J Psychiatry
Autors principals: Medina-Rodriguez, Eva M., Madorma, Derik, O’Connor, Gregory, Mason, Brittany L., Han, Dongmei, Deo, Sapna, Oppenheimer, Mark, Nemeroff, Charles B., Trivedi, Madhukar H., Daunert, Sylvia, Beurel, Eléonore
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7647050/
https://ncbi.nlm.nih.gov/pubmed/32731813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1176/appi.ajp.2020.19090960
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