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Pharmacological manipulation of cGMP and NO/cGMP in CNS drug discovery

The development of small molecule modulators of NO/cGMP signaling for use in the CNS has lagged far behind the use of such clinical agents in the periphery, despite the central role played by NO/cGMP in learning and memory, and the substantial evidence that this signaling pathway is perturbed in neu...

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Publicat a:Nitric Oxide
Autors principals: Hollas, Michael A., Aissa, Manel Ben, Lee, Sue H., Gordon-Blake, Jesse M., Thatcher, Gregory R.J.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7645969/
https://ncbi.nlm.nih.gov/pubmed/30394348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.niox.2018.10.006
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