Caricamento...

The mechanistic role of alpha-synuclein in the nucleus: impaired nuclear function caused by familial Parkinson’s disease SNCA mutations

Alpha-synuclein SNCA has been implicated in the etiology of Parkinson’s disease (PD); however, the normal function of alpha-synuclein protein and the pathway that mediates its pathogenic effect is yet to be discovered. We investigated the mechanistic role of SNCA in the nucleus utilizing isogenic hu...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Hum Mol Genet
Autori principali: Chen, Vivian, Moncalvo, Malik, Tringali, Dominic, Tagliafierro, Lidia, Shriskanda, Ahila, Ilich, Ekaterina, Dong, Wendy, Kantor, Boris, Chiba-Falek, Ornit
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7645704/
https://ncbi.nlm.nih.gov/pubmed/32954426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa183
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !