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Comparison of Sigma 1 Receptor Ligands SA4503 and PRE084 to (+)-Pentazocine in the rd10 Mouse Model of RP
PURPOSE: Sigma 1 receptor is a novel therapeutic target for retinal disease. Its activation, using a high-affinity, high-specificity ligand (+)-pentazocine ((+)-PTZ), rescues photoreceptor cells in the rd10 mouse model of RP. Here, we asked whether the robust retinal neuroprotective properties of (+...
Sparad:
| I publikationen: | Invest Ophthalmol Vis Sci |
|---|---|
| Huvudupphovsmän: | , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
The Association for Research in Vision and Ophthalmology
2020
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7645203/ https://ncbi.nlm.nih.gov/pubmed/33137196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.13.3 |
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