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Optimal timing for activation of Sigma 1 Receptor in the Pde6b(rd10)/J (rd10) mouse model of retinitis pigmentosa.
Sigma1 Receptor (Sig1R), a pluripotent modulator of cell survival, is a promising target for treatment of retinal degenerative diseases. Previously, we reported that administration of the high-affinity, high-specificity Sig1R ligand (+)-pentazocine, ((+)-PTZ) beginning at post-natal day 14 (P14) and...
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| Publicado no: | Exp Eye Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7808329/ https://ncbi.nlm.nih.gov/pubmed/33310057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2020.108397 |
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