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Sigma Receptor Ligand, (+)-Pentazocine, Suppresses Inflammatory Responses of Retinal Microglia

PURPOSE. To evaluate the effects of the σ 1 receptor (σR1) agonist, (+)-pentazocine, on lipopolysaccharide (LPS)–induced inflammatory changes in retinal microglia cells. METHODS. Retinal microglia cells were isolated from Sprague-Dawley rat pups. Cells were treated with LPS with or without (+)-penta...

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Detalhes bibliográficos
Main Authors: Zhao, Jing, Ha, Yonju, Liou, Gregory I., Gonsalvez, Graydon B., Smith, Sylvia B., Bollinger, Kathryn E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042630/
https://ncbi.nlm.nih.gov/pubmed/24812552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-12823
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