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Evaluation of Heat Effects on Transdermal Nicotine Delivery In vitro and In Silico Using Heat-Enhanced Transport Model Analysis
A combined experimental and computational model approach was developed to assess heat effects on drug delivery from transdermal delivery systems (TDSs) in vitro and nicotine was the model drug. A Franz diffusion cell system was modified to allow close control of skin temperature when heat was applie...
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| Publié dans: | AAPS J |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7644264/ https://ncbi.nlm.nih.gov/pubmed/32488395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-020-00457-w |
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