Evaluation of Heat Effects on Fentanyl Transdermal Delivery Systems Using In Vitro Permeation and In Vitro Release Methods

Experimental conditions that could impact the evaluation of heat effects on transdermal delivery systems (TDS) using an in vitro permeation test (IVPT) and in vitro release testing (IVRT) were examined. Fentanyl was the model TDS. IVPT was performed using Franz diffusion cell, heating lamp, and huma...

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Detalhes bibliográficos
Publicado no:J Pharm Sci
Main Authors: Zhang, Qian, Murawsky, Michael, LaCount, Terri D., Hao, Jinsong, Ghosh, Priyanka, Raney, Sam G., Kasting, Gerald B., Li, S. Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644256/
https://ncbi.nlm.nih.gov/pubmed/32702372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2020.07.013
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