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Evaluation of Heat Effects on Fentanyl Transdermal Delivery Systems Using In Vitro Permeation and In Vitro Release Methods

Experimental conditions that could impact the evaluation of heat effects on transdermal delivery systems (TDS) using an in vitro permeation test (IVPT) and in vitro release testing (IVRT) were examined. Fentanyl was the model TDS. IVPT was performed using Franz diffusion cell, heating lamp, and huma...

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Publicat a:J Pharm Sci
Autors principals: Zhang, Qian, Murawsky, Michael, LaCount, Terri D., Hao, Jinsong, Ghosh, Priyanka, Raney, Sam G., Kasting, Gerald B., Li, S. Kevin
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644256/
https://ncbi.nlm.nih.gov/pubmed/32702372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2020.07.013
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