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Evaluation of Heat Effects on Transdermal Nicotine Delivery In vitro and In Silico Using Heat-Enhanced Transport Model Analysis

A combined experimental and computational model approach was developed to assess heat effects on drug delivery from transdermal delivery systems (TDSs) in vitro and nicotine was the model drug. A Franz diffusion cell system was modified to allow close control of skin temperature when heat was applie...

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Bibliografische gegevens
Gepubliceerd in:AAPS J
Hoofdauteurs: La Count, Terri D., Zhang, Qian, Murawsky, Michael, Hao, Jinsong, Ghosh, Priyanka, Dave, Kaushalkumar, Raney, Sam G., Talattof, Arjang, Kasting, Gerald B., Li, S. Kevin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644264/
https://ncbi.nlm.nih.gov/pubmed/32488395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-020-00457-w
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