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Characterization of Temperature Profiles in Skin and Transdermal Delivery System When Exposed to Temperature Gradients In vivo and In Vitro

PURPOSE: Performance of a transdermal delivery system (TDS) can be affected by exposure to elevated temperature, which can lead to unintended safety issues. This study investigated TDS and skin temperatures and their relationship in vivo, characterized the effective thermal resistance of skin, and i...

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Detalhes bibliográficos
Publicado no:Pharm Res
Main Authors: Zhang, Qian, Murawsky, Michael, LaCount, Terri, Hao, Jinsong, Kasting, Gerald B., Newman, Bryan, Ghosh, Priyanka, Raney, Sam G., Li, S. Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630272/
https://ncbi.nlm.nih.gov/pubmed/28493100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-017-2171-x
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