Evaluation of Heat Effects on Fentanyl Transdermal Delivery Systems Using In Vitro Permeation and In Vitro Release Methods

Experimental conditions that could impact the evaluation of heat effects on transdermal delivery systems (TDS) using an in vitro permeation test (IVPT) and in vitro release testing (IVRT) were examined. Fentanyl was the model TDS. IVPT was performed using Franz diffusion cell, heating lamp, and huma...

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Veröffentlicht in:J Pharm Sci
Hauptverfasser: Zhang, Qian, Murawsky, Michael, LaCount, Terri D., Hao, Jinsong, Ghosh, Priyanka, Raney, Sam G., Kasting, Gerald B., Li, S. Kevin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644256/
https://ncbi.nlm.nih.gov/pubmed/32702372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2020.07.013
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