αv-Class integrin binding to fibronectin is solely mediated by RGD and unaffected by an RGE mutation

Fibronectin (FN) is an essential glycoprotein of the extracellular matrix; binds integrins, syndecans, collagens, and growth factors; and is assembled by cells into complex fibrillar networks. The RGD motif in FN facilitates cell binding­ and fibrillogenesis through binding to α5β1 and αv-class inte...

Full description

Saved in:
Bibliographic Details
Published in:J Cell Biol
Main Authors: Benito-Jardón, María, Strohmeyer, Nico, Ortega-Sanchís, Sheila, Bharadwaj, Mitasha, Moser, Markus, Müller, Daniel J., Fässler, Reinhard, Costell, Mercedes
Format: Artigo
Language:Inglês
Published: Rockefeller University Press 2020
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644020/
https://ncbi.nlm.nih.gov/pubmed/33141174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202004198
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items