αv-Class integrin binding to fibronectin is solely mediated by RGD and unaffected by an RGE mutation

Fibronectin (FN) is an essential glycoprotein of the extracellular matrix; binds integrins, syndecans, collagens, and growth factors; and is assembled by cells into complex fibrillar networks. The RGD motif in FN facilitates cell binding­ and fibrillogenesis through binding to α5β1 and αv-class inte...

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Publicat a:J Cell Biol
Autors principals: Benito-Jardón, María, Strohmeyer, Nico, Ortega-Sanchís, Sheila, Bharadwaj, Mitasha, Moser, Markus, Müller, Daniel J., Fässler, Reinhard, Costell, Mercedes
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644020/
https://ncbi.nlm.nih.gov/pubmed/33141174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202004198
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