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αv-Class integrin binding to fibronectin is solely mediated by RGD and unaffected by an RGE mutation
Fibronectin (FN) is an essential glycoprotein of the extracellular matrix; binds integrins, syndecans, collagens, and growth factors; and is assembled by cells into complex fibrillar networks. The RGD motif in FN facilitates cell binding and fibrillogenesis through binding to α5β1 and αv-class inte...
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| Published in: | J Cell Biol |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Rockefeller University Press
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7644020/ https://ncbi.nlm.nih.gov/pubmed/33141174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202004198 |
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