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The fibronectin synergy site re-enforces cell adhesion and mediates a crosstalk between integrin classes
Fibronectin (FN), a major extracellular matrix component, enables integrin-mediated cell adhesion via binding of α5β1, αIIbβ3 and αv-class integrins to an RGD-motif. An additional linkage for α5 and αIIb is the synergy site located in close proximity to the RGD motif. We report that mice with a dysf...
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| Vydáno v: | eLife |
|---|---|
| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
eLife Sciences Publications, Ltd
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5279944/ https://ncbi.nlm.nih.gov/pubmed/28092265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.22264 |
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