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The RGD motif in fibronectin is essential for development but dispensable for fibril assembly
Fibronectin (FN) is secreted as a disulfide-bonded FN dimer. Each subunit contains three types of repeating modules: FN-I, FN-II, and FN-III. The interactions of α5β1 or αv integrins with the RGD motif of FN-III repeat 10 (FN-III(10)) are considered an essential step in the assembly of FN fibrils. T...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2007
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2064432/ https://ncbi.nlm.nih.gov/pubmed/17591922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200703021 |
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