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A Method to Determine the Mode of Binding for GCPII Inhibitors using Bio-Layer Interferometry
The rapid dilution of the enzyme-inhibitor complex assay to monitor the recovery of enzyme activity is a well-established assay to determine the reversibility of inhibition. Our laboratory has previously employed this method to ascertain the reversibility of known GCPII targeting agents. Due to the...
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| Publicat a: | J Enzyme Inhib Med Chem |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7643579/ https://ncbi.nlm.nih.gov/pubmed/26873576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/14756366.2015.1132208 |
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