N-Acetyl Cysteine Abrogates Silver-Induced Reactive Oxygen Species in Human Cells Without Altering Silver-based Antimicrobial Activity

Silver-based antimicrobials are widely used topically to treat infections associated with multi-drug resistant (MDR) pathogens. Expanding this topical use to aerosols to treat lung infections requires understanding and preventing silver toxicity in the respiratory tract. A key mechanism resulting in...

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Veröffentlicht in:Toxicol Lett
Hauptverfasser: Shah, Kush N., Shah, Parth N., Mullen, Andrew R., Chen, Qingquan, Southerland, Marie R., Chirra, Bhagath, DeBerardinis, Ralph J., Cannon, Carolyn L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7643162/
https://ncbi.nlm.nih.gov/pubmed/32659471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2020.07.014
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