EPEC Recruits a Cdc42-Specific GEF, Frabin, To Facilitate PAK Activation and Host Cell Colonization

Enteropathogenic Escherichia coli (EPEC) is an extracellular pathogen that tightly adheres to host cells by forming “actin pedestals” beneath the bacteria, a critical step in pathogenesis. EPEC injects effector proteins that manipulate host cell signaling cascades to trigger pedestal assembly. We ha...

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Detaylı Bibliyografya
Yayımlandı:mBio
Asıl Yazarlar: Singh, Vikash, Hume, Peter J., Davidson, Anthony, Koronakis, Vassilis
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7642674/
https://ncbi.nlm.nih.gov/pubmed/33144373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01423-20
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