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EPEC Recruits a Cdc42-Specific GEF, Frabin, To Facilitate PAK Activation and Host Cell Colonization

Enteropathogenic Escherichia coli (EPEC) is an extracellular pathogen that tightly adheres to host cells by forming “actin pedestals” beneath the bacteria, a critical step in pathogenesis. EPEC injects effector proteins that manipulate host cell signaling cascades to trigger pedestal assembly. We ha...

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Bibliografiset tiedot
Julkaisussa:mBio
Päätekijät: Singh, Vikash, Hume, Peter J., Davidson, Anthony, Koronakis, Vassilis
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7642674/
https://ncbi.nlm.nih.gov/pubmed/33144373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01423-20
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