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CUDC-907 enhances TRAIL-induced apoptosis through upregulation of DR5 in breast cancer cells

CUDC-907 is a novel dual-acting inhibitor of phosphoinositide 3-kinase (PI3K) and histone deacetylase (HDAC). In this study, we aimed to explore the anticancer effects of CUDC-907 on human breast cancer cells. Our results showed that CUDC-907 effectively inhibited breast cancer cell proliferation. F...

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Detalhes bibliográficos
Publicado no:J Cell Commun Signal
Main Authors: Li, Zhao-Jun, Hou, Ya-Jun, Hao, Gang-Ping, Pan, Xiao-Xuan, Fei, Hong-Rong, Wang, Feng-Ze
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7642015/
https://ncbi.nlm.nih.gov/pubmed/32200503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-020-00558-3
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