c-Jun NH(2)-terminal kinase-dependent upregulation of DR5 mediates cooperative induction of apoptosis by perifosine and TRAIL

BACKGROUND: Perifosine, an alkylphospholipid tested in phase II clinical trials, modulates the extrinsic apoptotic pathway and cooperates with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to augment apoptosis. The current study focuses on revealing the mechanisms by which perifosi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Fu, Lei, Lin, Yi-Dan, Elrod, Heath A, Yue, Ping, Oh, Youtake, Li, Bo, Tao, Hui, Chen, Georgia Z, Shin, Dong M, Khuri, Fadlo R, Sun, Shi-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018404/
https://ncbi.nlm.nih.gov/pubmed/21172010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-315
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados