A tumour suppressive relationship between mineralocorticoid and retinoic acid receptors activates a transcriptional program consistent with a reverse Warburg effect in breast cancer

BACKGROUND: The role of nuclear receptors in both the aetiology and treatment of breast cancer is exemplified by the use of the oestrogen receptor (ER) as a prognostic marker and treatment target. Treatments targeting the oestrogen signalling pathway are initially highly effective for most patients....

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Vydáno v:Breast Cancer Res
Hlavní autoři: Doan, Tram B., Cheung, Vanessa, Clyne, Colin D., Hilton, Heidi N., Eriksson, Natalie, Young, Morag J., Funder, John W., Muscat, George E. O., Fuller, Peter J., Clarke, Christine L., Graham, J. Dinny
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641839/
https://ncbi.nlm.nih.gov/pubmed/33148314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-020-01355-x
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