Use of Phage Display to Identify Novel Mineralocorticoid Receptor-Interacting Proteins

The mineralocorticoid receptor (MR) plays a central role in salt and water homeostasis via the kidney; however, inappropriate activation of the MR in the heart can lead to heart failure. A selective MR modulator that antagonizes MR signaling in the heart but not the kidney would provide the cardiova...

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Vydáno v:Mol Endocrinol
Hlavní autoři: Yang, Jun, Fuller, Peter J., Morgan, James, Shibata, Hirotaka, McDonnell, Donald P., Clyne, Colin D., Young, Morag J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2014
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414797/
https://ncbi.nlm.nih.gov/pubmed/25000480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2014-1101
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