A carregar...

Identification of Ligand-Selective Peptide Antagonists of the Mineralocorticoid Receptor Using Phage Display

The mineralocorticoid receptor (MR) is a member of the nuclear receptor superfamily. Pathological activation of the MR causes cardiac fibrosis and heart failure, but clinical use of MR antagonists is limited by the renal side effect of hyperkalemia. The glucocorticoid cortisol binds the MR with equi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Yang, Jun, Chang, Ching-yi, Safi, Rachid, Morgan, James, McDonnell, Donald P., Fuller, Peter J., Clyne, Colin D., Young, Morag J.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417296/
https://ncbi.nlm.nih.gov/pubmed/21106883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0193
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!