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A tumour suppressive relationship between mineralocorticoid and retinoic acid receptors activates a transcriptional program consistent with a reverse Warburg effect in breast cancer

BACKGROUND: The role of nuclear receptors in both the aetiology and treatment of breast cancer is exemplified by the use of the oestrogen receptor (ER) as a prognostic marker and treatment target. Treatments targeting the oestrogen signalling pathway are initially highly effective for most patients....

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Doan, Tram B., Cheung, Vanessa, Clyne, Colin D., Hilton, Heidi N., Eriksson, Natalie, Young, Morag J., Funder, John W., Muscat, George E. O., Fuller, Peter J., Clarke, Christine L., Graham, J. Dinny
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641839/
https://ncbi.nlm.nih.gov/pubmed/33148314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-020-01355-x
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