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Strict conformational demands of RNA cleavage in bulge-loops created by peptidyl-oligonucleotide conjugates
Potent knockdown of pathogenic RNA in vivo is an urgent health need unmet by both small-molecule and biologic drugs. ‘Smart’ supramolecular assembly of catalysts offers precise recognition and potent destruction of targeted RNA, hitherto not found in nature. Peptidyl-oligonucleotide ribonucleases ar...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7641753/ https://ncbi.nlm.nih.gov/pubmed/33010175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa780 |
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